8. Seldane
Seldane is also among the drugs pulled from the market. Seldane, a popular antihistamine, was brought to market in 1985 to treat allergies without causing drowsiness. It may not have caused this particular side effect, but it caused others.
The FDA sought a recall from the manufacturer, Hoechst Marion Roussel (now Aventis), after cases of cardiac arrhythmia were discovered in patients taking Seldane with other drugs. More than 100 million patients worldwide took it as of 1990, which makes it one of the most notable recalls in history.
Following Seldane’s withdrawal, the manufacturer introduced Allegra on the market, a drug pretty similar to Seldane but without its side effects.
